Endocrine Abstracts

Glycogen storage disease, which is a metabolic disorderof glycogen storage, affecting 1 in 20000-40000 ive births. This is a case of yound adolescent female with glycogen storage disease type1b, presented with lactic acidosis and managed in ITU.18 years old femae from Honk kong, student in a college, admitted to a dgh hospital with fever, vomiting and abdominal pain for a week. examination showed severe features of dehydratio...

Glycogen storage disease, which is a metabolic disorderof glycogen storage, affecting 1 in 20000-40000 ive births. This is a case of yound adolescent female with glycogen storage disease type1b, presented with lactic acidosis and managed in ITU.18 years old femae from Honk kong, student in a college, admitted to a dgh hospital with fever, vomiting and abdominal pain for a week. examination showed severe features of dehydratio...

30 years old female with history of sinusitis, anxiety states, diagnosed with relapsing multiple sclerosis from May 2005, initially had abnormal sensation and weakness of left side of body with MRI finding of demyelinating lesion in the cervical cord, treated with i/v methyl prednisolone with good recovery. Unfortunately had multiple relapses, therefore treated with two doses of Alemtuzumab since June 2012, presented with shakiness and a rash in her neck in July 2012. Clinical...

61 years old female with multiple comorbidities such as ckd-3, Trans abdominal hysterectomy and oophorectomy for endometrial cancer, complicated by entero-cutaneous fistula, ileal conduit and cholecystectomy.She presented with generally unwell, nausea, vomiting, confusion.On Examination she was bradycardic, low gcs, hypotensive and hypothermic.The metabolic causes for confusion was excluded, anion gap was nor...

A 73-year-old female, fit and well otherwise, was not any regular medications, was diagnosed with choroidal melanoma in 2010, and enucleated, subsequently had DTIC for multiple metastasis in 2014. She also received ipilimumab for 3 months as second line treatment for metastases. Presented to neurosurgeons with cold intolerance and dizzy spells, random cortisol was <30, started on dexamethasone 1 mg twice daily. Also had a low TSH of 0.71 with low free T4. Short ...

Case History: A 69-year-old woman with bipolar schizoaffective disorder of 11 year’s duration and recent diagnosis of atrial fibrilation was admitted with acute onset of delirium, lethargy, shakiness and confusion. On admission, the patient was restless and non-compliant. Her skin was warm and sweaty, clinically dehydrated. Her heart rate ranging between 75 and 100 /min. The rhythm was irregular, consistent with atrial fibrillation on ECG and was afebrile. She was oriented to ...

Introduction: Traditionally the long synacthen test (LST) is used in some centres to assess hypothalamic/ pituitary and adrenal (HPA) axis. Evidence that it offers advantage over short synacthen test (SST) is lacking. Whilst changing our local protocol we evaluated 27 patients who had both tests in our trust. We compared the impact of the results in clinical decision making.Results: Mean age was 53 years. The indications for th...

Introduction: Traditionally the long synacthen test (LST) is used in some centres to assess hypothalamic/ pituitary and adrenal (HPA) axis. Evidence that it offers advantage over short synacthen test (SST) is lacking. Whilst changing our local protocol we evaluated 27 patients who had both tests in our trust. We compared the impact of the results in clinical decision making.Results: Mean age was 53 years. The indications for th...

We present the case history of a 33-year-old male with Noonan syndrome diagnosed at 2 months of age, as he had typical facial features (hypertelorism, ptosis, low set ears, and small pointed chin), a heart murmur and bilateral cryptorchidism. At 22 months he underwent patent ductus arteriosus closure and at 24 months, the left testis was excised, for testicular torsion. He had learning difficulties and attended a special needs school and was intermittently reviewed in the paed...